Showing posts with label Thyroid. Show all posts
Showing posts with label Thyroid. Show all posts
Thyroid Case



Name:
Age/Sex:
Occupation:
Residence:

Presenting Complaints

Swelling in front of Neck   Duration
  
History of Presenting Illness

  • H/O Swelling

  • Site
  • Duration
  • Onset
  • Progress of the swelling:
  • Associated

  • H/O Pain

  • Site
  • Duration
  • Onset
  • Character: Usually dull-aching
  • Radiation
  • Relieving factors
  • Aggravating factors

R/O Pressure Symptoms

  • H/O Difficulty in Swallowing: Solid or liquid  
  • H/O Difficulty in breathing  
  • H/O Hoarseness of Voice
  • H/O Drooping of the upper eyelid (ptosis), Absence of sweating of the face (anhidrosis)

R/O Hyperthyroidism
  
Primary Hyperthyroidism (Mainly CNS Symptoms)
  • H/O Tremors
  • H/O Irritability on slight provocation
  • H/O Insomnia
  • H/O Muscle Weakness

Primary Hyperthyroidism (Eye Symptoms)
  • H/O Bulging of eyes

  • Duration
  • Progress
  • History of redness of eye and watering
  • History of double vision
  • Loss of vision

Secondary Hyperthyroidism (Mainly Cardiovascular Symptoms)

  • H/O Palpitations
  • H/O Ectopic Beats
  • H/O Chest pain
  • H/O Breathlessness on exertion

Hyperthyroidism (Sympathetic Hyperstimulation)
  • H/O Increased sweating
  • H/O Heat intolerance  

Hyperthyroidism (Increased BMI)
  • H/O Increased Appetite
  • H/O Weight Loss

Hyperthyroidism (GI)
  • H/O Increased frequency of passing stools



  • 62 year old Man from a remote village had come with complaints of swellings in neck from past 1 year. The swellings were painless.
  • He had a history of hoarseness of voice, loss of appetite and significant loss of weight.
  • There was an irregular mass in the midline which moves on swallowing.
  • Multiple large fixed nodes were palpable (Left Side - Mid jugular, lower jugular large nodes and Right Side - Multiple small nodes, middle and lower jugular group)
  • On palpation of left side of neck, Berry's sign was positive (Berry’s sign is the absence of carotid pulsation on palpation) 
  • FNAC revealed Papillary Thyroid Carcinoma.


Left Side of Neck



Right Side of Neck

What are the manifestations in Eye in cases of Thyrotoxicosis due to Graves Disease?
The condition is otherwise called Graves opthalmopathy. It is an autoimmune inflammatory disorder affecting the orbit around the eye, characterized by upper eyelid retraction, lid lag, swelling (edema), redness (erythema), conjunctivitis, and bulging eyes (proptosis).

What are various signs seen in Graves opthalmopathy?
  • Rosenbach's sign
  • Stellwag's sign
  • Dalrymple's sign
  • Von Graef's Sign
  • Joffroy's sign
  • Moebius' Sign
What is the cause of development of Graves Opthalmopathy?
The autoantibodies target the fibroblasts in the eye muscles, and those fibroblasts can also differentiate into fat cells (adipocytes). Fat cells and muscles expand and become inflamed causing buldging of eyes. Veins become compressed, and are unable to drain fluid, causing edema.




What percentage of Graves disease patients are affected?
Graves opthalmopathy affects between 25-50% of patients with Graves' disease.

How is Graves opthalmopathy treated?
Various management options include:

  • Topical Lubrication
  • Corticosteroids
  • Thyroidectomy
  • Tarsorraphy
  • Treatment with selenium is effective in mild cases (Ref)
  • Orbital Radiotherapy


Related Links:






Thyroidectomy steps and video

  1. GA, head ring, shoulder bolster to extend the neck
  2. Transverse incision 2 cm above sternal notch
  3. Skin, subcutaneous fat and platysma are incised transversely
  4. Investing fascia and connective tissue between the sternohyoid and sternothyroid muscles are incised vertically. 
  5. Usually the strap muscles are not divided, but this may be necessary in case of large got results.
  6. If they do need to be divided this should be done as high as possible (ie above the point of entry of the ansa cervicalis nerve branches) to prevent denervation and muscle wasting
  7. Pretracheal fascia around the thyroid is incised
  8. Thyroid lobe is mobilised
  9. RLN is identified
  10. Traditionally, the superior thyroid artery is tied off close to the thyroid gland (to protect the ELN) and the inferior thyroid artery is tied off laterally away from the thyroid (to protect the RLN). However, many surgeons now divide the branches of the inferior thyroid artery individually on the gland to protect the blood supply to the parathyroids
  11. If a parathyroid is excised, it can be cut up and implanted in the sternomastoid. The majority of these continue to function normally
  12. Thyroid gland is excised
  13. Haemostasis, suction drain, closure in layers (approximate strap muscles and platysma), skin closure

References
Chalmers, Claire Ritchie. “MRCS Part A: Essential Revision Notes Book 2
(Buy Now)
Thyroidectomy Video with Steps

Pharmacologic hypothyroidism
Pharmacologic hypothyroidism
Causes of Pharmacologic hypothyroidism
Causes of Pharmacologic hypothyroidism
Amiodarone and Thyroid
Amiodarone and Thyroid
Lithium and Thyroid
Lithium and Thyroid
Cytokines and thyroid
Cytokines and thyroid
   




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Lymphatic drainage of thyroid gland and lymph node levels in neck
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Lymphatic System of Thyroid
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Lymph node levels of neck
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Source of Nodal metastasis in neck
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Classification of nodal dissections of neck
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Types of MRND
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Indication of prophylactic neck dissection in thyroid ca
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Indication of prophylactic neck dissection in thyroid ca 2
 





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Blood supply of thyroid
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Arterial supply of thyroid
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Blood supply of thyroid diagram
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Venous drainage of thyroid
 




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